Reliable Aseptic Filling Machines Designed for Four Barrel Use

2025-05-23 14:16:32 glzon


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Reliable Aseptic Filling Machines for Four-Barrel Use


Overview

The Aseptic Filling Machine for Four Barrel Use is a high-capacity, precision-engineered solution designed for the aseptic filling of liquids, semi-solids, and viscous products in pharmaceutical, biotech, food, and beverage industries. With a four-barrel configuration, it delivers parallelized filling processes, maximizing efficiency while maintaining strict sterility and compliance with global standards (e.g., cGMP, ISO, ASEP).


Key Features

Four-Barrel Parallel Filling

  • High Throughput: Simultaneously fill up to 4 products or linese777乐彩线路检测 at once, doubling or quadrupling production capacity compared to single-barrel systems.

  • Independent Control: Each barrel operates with its own servo-driven pumps, valves, and weight cells for precise, individualized filling.

Aseptic & Sterility Assurance

  • SIP/COP Capability: Steam-in-place (SIP) and clean-out-of-place (COP) functions for automated sterilization of barrels, hoses, and nozzles.

  • Isolator Technology:e777乐彩线路检测 Optional RABS (Restricted Access Barrier Systems) or fully enclosed isolator designs to prevent contamination.

  • A-Class Cleanroom Compatibility:e777乐彩线路检测 Constructed with stainless steel 316L and polished surfaces (Ra < 0.4 μm).

Precision Filling Technology

  • Weight-Based Filling: Integrated load cells with ±0.1% accuracy for consistent fill volumes.

  • Nozzle Design:e777乐彩线路检测 Customizable contact/non-contact nozzles for vials, bottles, pouches, or syringes.

  • Foam Control: Vacuum or nitrogen purging to minimize product foaming during filling.

Flexibility & Versatility

  • Multi-Product Handling: Quick changeover between different products or container types (e.g., glass vials, plastic bottles, bags).

  • Fill Volume Range: 1–500 ml per container, adjustable via HMI (Human-Machine Interface).

  • Viscosity Handling: Suitable for low-viscosity (water-like) to high-viscosity (syrups, creams) products.

Automation & Integration

  • PLC & HMI Controls: Touchscreen interface for recipe storage, real-time monitoring, and remote troubleshooting.

  • Robotic Integration: Compatible with pick-and-place robots for automated container loading/unloading.

  • Data Logging: Ethernet/IP connectivity for traceability, batch reporting, and compliance with 21 CFR Part 11.

Safety & Compliance

  • Locked Seals: Automated clamp closures and pressure sensors to ensure leak-proof operations.

  • Particle Detection: Inline laser or vision systems to reject contaminated containers.

  • Validation Pack: IQ/OQ/PQ documentation, calibration certificates, and performance protocols included.


Optional Enhancements

  • Stopper/Cap Placement:e777乐彩线路检测 Automated crimping, screw capping, or stopper insertion modules.

  • Labeling Systems: Inline printers/applicators for expiration dates, lot numbers, or barcodes.

  • Nitrogen Flushing: Overhead or nozzle-based purging to preserve product integrity post-fill.

  • Weight Checking:e777乐彩线路检测 Inline checkweighers for 100% weight verification.


Applications

  • Pharmaceuticals: Sterile injectables, ophthalmic solutions, vaccines, and oral liquids.

  • Biotech: Cell cultures, protein solutions, and gene therapy vectors.

  • Food & Beverage:e777乐彩线路检测 Juices, dairy products, sauces, and ready-to-eat meals in aseptic pouches.

  • Chemicals:e777乐彩线路检测 Specialty chemicals requiring aseptic handling (e.g., cosmetics, industrial fluids).


Technical Specifications

  • Filling Speed: Up to 1,200 containers/houre777乐彩线路检测 (per barrel) depending on product and container type.

  • Fill Accuracy:e777乐彩线路检测 ±0.2–0.5% (adjustable via HMI).

  • Materials:e777乐彩线路检测 Stainless steel 316L, silicone gaskets, and certified cleanroom polymers.

  • Power: 220V/380V/480V (customizable), 10–20 kW.

  • Footprint: Compact design (e.g., 3m x 2m x 2.5m) with modular expansion options.

  • Environment:e777乐彩线路检测 Designed for Class A–D cleanrooms or ISO 5–8 environments.


Benefits

  1. Productivity:e777乐彩线路检测 Four-barrel design reduces cycle time and increases output without compromising sterility.

  2. Flexibility:e777乐彩线路检测 Supports multi-product runs and container formats with quick changeovers.

  3. Compliance:e777乐彩线路检测 Full traceability, validation packages, and cGMP-compliant design.

  4. Low Risk: SIP/COP sterilization and isolator options minimize cross-contamination.

  5. ROI:e777乐彩线路检测 High throughput and reduced labor costs lead to rapid return on investment.


Why Choose This Machine?

Engineered for speed, precision, and sterility, this four-barrel aseptic filler combines parallel processing with advanced automation to meet the demands of high-volume production while ensuring patient safety and product integrity. Perfect for manufacturers requiring scalable, reliable, and compliant aseptic filling solutions.


Ready to optimize your aseptic filling line? Contact us for a customized quote and workflow analysis!

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